Best Weight Loss Pills

Last Updated April 13, 2021Posted in Health & Beauty

Best Weight Loss Pills

With so many weight loss pills and diet supplements available, picking a high-quality product that actually works can feel like an overwhelming task.

We’ve said a lot about diet pills in the past. A lot of it has been negative. Of course, when a residential weight loss camp – the kind of place that focuses on getting results the hard (it’s pronounced “right”) way – tells you that an alternative method is bunk, you’re likely to take it with a grain of salt.

So today, we’re going to take a closer look at the various medications and pills out there, and give you an honest-to-goodness summary on what works, what doesn’t, and why.

Are weight loss pills safe?

The drugs that have been approved by the FDA have gone through extensive clinical trials and have a very low side-effect profile. But as with all medications and supplements, diet pills can come with unpleasant or damaging side effects and risks—even if they’ve been tested in clinical trials and approved by the FDA.

Another warning: Pharmacy and supplement store shelves are lined with weight-loss pills that have limited—or zero—research behind them, so the long-term effects of taking the drugs can be unclear. Meanwhile, some options are plain unsafe. In fact, certain weight-loss pills that were initially approved by the FDA, such as dexfenfluramine (Redux) and fenfluramine (Fen-Phen), were only discovered to be associated with scary health risks (and had their FDA approvals withdrawn) after being released on the market.

5 Best Weight Loss Pills of 2021:

NameMain IngredientBenefits
LeanbeanPatented goBHB formulaPowerful BHB
Alli (orlistat)Gelatin, iron oxide, microcrystalline celluloseCompostable
ShredFIERCEGreen tea extract, garcinia cambogia, and raspberry ketonesPhytoChoice
TrimToneNatural ingredients, pure and safe 100% Made in the USASuppress appetite
Green TeaGreen tea leaf extract is packed with antioxidants and EGCGSupports detox program

1. Leanbean: Best Weight Loss Pills For Women

Leanbean: Best Weight Loss Pills For Women

LeanBean is our top choice for the best fat burner for women. This powerful weight loss pill uses all-natural ingredients to help you burn stubborn fat, kickstart your metabolism, and suppress your appetite. LeanBean has rave reviews from thousands of women across the world, including many instagram models and influencers that swear by its effectiveness.

One of the key ingredients inside the LeanBean formula is an appetite suppressant called Glucomannan. This soluble fiber makes you feel fuller between meals, allowing you to reduce calorie intake and burn fat more easily.

LeanBean uses a safe blend of natural thermogenics and minerals to boost your body’s metabolism. By increasing your metabolic rate, your body will use your body fat more often as a fuel source.

If you’re a woman looking for a weight loss pill that gets results, LeanBean is a great option to consider. With a 90-day money back guarantee, you have virtually nothing to lose by giving it a try.

  • Designed for the female body
  • Includes 11 all-natural ingredients that are safe and free of side effects
  • Low in stimulants
  • Doesn’t contain any pure caffeine
  • 90-Day money back guarantee

2. Alli (orlistat)

Alli (orlistat)

Alli is the brand name for the drug orlistat. It is one of the most popular weight loss pills.

Orlistat is available as a prescription drug and also sold over the counter. It works by preventing the body from breaking down of some of the fat that people eat. When the intestines absorb less fat, weight loss may occur.

A review of 11 studies indicated that orlistat might increase weight loss by a small amount. The review found that those who took orlistat lost an average of 2.9 percent more weight than those who did not take the drug.

Orlistat may cause a change in bowel habits. People taking orlistat may experience side effects, such as diarrhea, stomach pain, and difficulty controlling bowel movements.

  • One of the few medically proven weight loss supplements
  • An OTC form of a drug that’s usually only available by prescription
  • Just one active ingredient
  • Suitable for people with a BMI of over 28
  • Widely available

3. ShredFIERCE – Best Weight Loss Pills for Men

ShredFIERCE - Best Weight Loss Pills for Men

ShredFIERCE is one of the best weight loss pills for men on the market. This supplement is a masculine option designed for gym-goers looking for quick weight loss. We’ve included it in this roundup due to its focus on boosting metabolism.

And here’s why.

In the ShredFIERCE formula, you’ll find six ingredients with clear links to the increased metabolism of fats and macronutrients. And what’s more, the doses are clearly and transparently labelled, rather than hiding within proprietary blends as is so common with supplements.

ShredFIERCE Brand Highlights Packed with metabolic boosters to streamline fat storage and usage.

  • No proprietary blend: Full ingredient transparency
  • This fat burner is geared towards men
  • Designed to help your body burn fat more efficiently
  • Optimised 300mg dose of acetyl l-carnitine per day

4. TrimTone: Most Effective Thermogenic Fat Burner


TrimTone is a fat burner for women that’s designed to burn fat, reduce appetite, and boost metabolism. The best part about TrimTone is it uses 100% natural ingredients, meaning there is no prescription required.

And it works by stimulating thermogensis inside your body, converting stored fat into energy. It literally turns your body into a fat burning machine, allowing you to burn calories even while you rest. By burning through stubborn body fat 24 hours a day, you will be able to reach your weight loss goals quicker than ever.

TrimTone also helps you curb cravings with appetite suppressing ingredients. By having better control over your cravings, you’ll be able to avoid unnecessary calories for a slimmer waistline.

Overall, TrimTone prides itself in only using high quality ingredients, free of fillers and unnecessary ingredients that you can hardly pronounce.

  • Manufactured in the United States
  • Fast Results Seen In Just Weeks
  • 100% Natural Ingredients, Free of Side Effects
  • Effective Fat Burner and Appetite Suppressant
  • 100 Day Money Back Guarantee

5. Green Tea (or Green Tea Extract when in pill form)

Green Tea

Green Tea originates from China, and is made from the leaves of the camellia sinensis, an evergreen shrub more commonly referred to simply as a “tea plant”. It contains a number of beneficial antioxidants and bioactives, including small amounts of caffeine.

The reason it is cited as a weight loss aid however, is one of these in particular called epigallocatechin gallate, epigallocatechin-3-gallate, or simply EGCG. This is also found in black tea which is made from the same leaves of the same plant – but the concentration is much lower due to the withering / drying processes during preparation.

EGCG when combined with caffeine and other ingredients naturally found in Green Tea has been shown to boost metabolism, as well as increase the effects of specific hormones that trigger the breakdown of fat cells for fuel. There is even some evidence that it helps to suppress appetite.

As a result of these findings, tea has found its’ way into countless other forms of packaging – including quite a few of the natural weight loss supplements you’ll find on herbal shelves.

  • Green tea hits the body in several different ways
  • It is full of powerful antioxidants the body needs to function properly
  • Boosts metabolism
  • Reduce appetite

Do any weight loss pills really work?

When it comes to weight loss, there is no shortage of pills, drinks, and supplements claiming to help the weight fall off. But do weight loss pills help, and are they safe?

The best weight loss pills may contain one or more active ingredients intended to increase fat burning, decrease appetite, or reduce absorption of fat.

Not all weight loss pills and supplements are created equal. Certain pills may cause unpleasant side effects while others may not be proven to result in weight loss.

Best Weight Loss Pills FAQ

What are the differences between OTC and prescription weight loss medications?

The medicines currently available are appetite suppressants in some form. They help control hunger and cravings, so you can stick to your nutrition and exercise plan. The only FDA-approved over-the-counter medicine for weight loss is Alli (orlistat). This blocks the body’s ability to absorb fats. The remainder of over-the-counter products are considered supplements.

They are not regulated by the FDA and do not have proper studies to confirm their safety and effectiveness. There are prescription medicines that help with weight loss: Qsymia (phentermine/topiramate), Contrave (bupropion/naltrexone), and Saxenda (liraglutide). These are only available through a prescription from a healthcare provider.

Each one has certain indications based on the medical evaluation. Obesity is a chronic disease that caused by multiple factors and is the leading risk factor for numerous other medical conditions. Therefore, it is important that your healthcare provider works with you to ensure you are on the safest and most effective medication.

What is the connection between antidepressant medication and weight loss?

Many antidepressants are weight-positive (cause weight gain), some are weight-neutral, and at least one is weight-negative (cause weight loss).

When starting an antidepressant, it is a good idea to speak with a healthcare provider about the different options and find a medication that will not cause weight gain. Antidepressants are broken down into categories: selective serotonin reuptake inhibitors (SSRIs), serotonin and norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants, monoamine oxidase inhibitors (MAO inhibitors), and others.

Medications within each of these categories can cause weight gain. In the SSRI group, Paroxetine shows the highest associated weight gain. Other SSRIs, including Citalopram (Celexa), Escitalopram (Lexapro), Fluoxetine (Prozac), and Sertraline (Zoloft), have variable effects on weight, and some do not show weight gain until after six months of use. Weight-positive medications in the tricyclic antidepressant category include Amitriptyline, Doxepin, and Imipramine.

Desipramine, Nortriptyline, and Protriptyline have variable effects on weight. Bupropion (Wellbutrin), an aminoketone, is considered weight-negative and is prescribed both to assist in weight loss and to treat depression. However, people respond to antidepressants differently. If a person’s depression can be controlled with a weight-negative or weight-neutral antidepressant, they will likely take the medication more consistently, resulting in better efficacy.

Which weight loss pills are known for suppressing appetite?

The following FDA-approved medications suppress appetite: Liraglutide (Saxenda™), Naltrexone-Bupropion (Contrave™), Phentermine-Topiramate (Qysmia™), as well as these stimulants: benzphetamine (Didrex™), diethylpropion (Tenuate™), phentermine (Adiphex-P™, ProFast™), and phendimetrazine.

Each medicine impacts appetite differently. Liraglutide is an injectable medication that acts on hormones from the gut that send signals to the brain to make you feel full quicker and decrease hunger signals. Lorcaserin is an oral medication that makes you feel full sooner by acting on serotonin, a neurotransmitter, in a part of the brain that controls appetite.


With there being 5 great weight loss pills and fat-burners to choose from, it is dependent on preference, gender and lifestyle what will work best for each individual.

There are numerous benefits of each pill, all providing more than one weight loss and fat burning function. Some work quicker and more effectively than others. However, all show real results and should be consumed alongside a balanced nutritious diet and regular exercise to maximise results.

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